use three-vessel OCT in patients with MINOCA to identify vascular causes, at
the time of diagnostic angiography. These include plaque disruption (rupture,
erosion or calcified nodule with thrombus), dissection and coronary artery
assess plaque composition in patients with MINOCA using OCT.
assess myocardial abnormalities in patients with MINOCA using CMR. This
includes areas of late gadolinium enhancement and myocardial edema. Multiple
CMR techniques will be used to identify edema, using a standardized imaging
synthesize findings of OCT and CMR to identify the underlying etiology of
MINOCA in women and men.
proportion of patients for whom an etiology can be clearly identified after
combining OCT and CMR.
create a clinical prediction model for plaque disruption on OCT in patients
investigate whether patients with MINOCA have higher pre-event stress levels
than patients with MI and obstructive CAD.
identify any sex differences in the primary and secondary outcomes.
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